Folic Acid

Folic acid is a synthetic form of vitamin B9, an essential nutrient for many functions in the human body. Also known as folate when found naturally in foods, this vitamin plays a vital role in the formation of new cells, especially in the development of the nervous system in babies during pregnancy.

Folic acid is widely recommended for women who are pregnant or trying to conceive, as its deficiency can cause severe problems with fetal development, such as neural tube defects.

Importance of Folic Acid in Pregnancy

Folic acid is widely known for its importance in pregnancy. Its supplementation is recommended for women who plan to become pregnant and during the first months of pregnancy. This is because folic acid is essential for the proper development of the fetus, especially in the formation of the neural tube, which gives rise to the brain and spinal cord.

Folic acid deficiencies during early pregnancy can lead to congenital malformations such as spina bifida and anencephaly. For this reason, many experts recommend that folic acid supplementation begin before conception to ensure that a woman’s body has adequate levels of this vitamin.

Health Benefits of Folic Acid

While folic acid is widely associated with gestational health, its benefits go far beyond that. Here are some of the main benefits of folic acid:

  1. Prevention of Anemia: Folic acid helps in the production of red blood cells, which prevents megaloblastic anemia, a type of anemia characterized by abnormally large blood cells.
  2. Cardiovascular Health: Folic acid helps reduce levels of homocysteine, an amino acid that, in excess, can damage blood vessels and increase the risk of cardiovascular disease.
  3. Nervous System Support: In addition to its role in fetal development, folic acid is important for maintaining mental and cognitive health, helping to prevent neurological problems.
  4. Reduced Cancer Risks: Studies indicate that folate deficiency may be associated with a higher risk of certain cancers, such as colon cancer and breast cancer.

Natural Sources of Folic Acid

Folic acid can be found in both foods and vitamin supplements. When present naturally in food, it is called folate. Some of the main sources of folate in the diet include:

  • Green leafy vegetables (spinach, broccoli, kale)
  • Citrus fruits (orange, lemon, tangerine)
  • Legumes (beans, lentils, chickpeas)
  • Fortified cereals
  • Avocado
  • Nuts and seeds

Although food can provide folate in adequate amounts for many people, pregnant women or women of childbearing age often require supplementation, as the need for folic acid increases significantly during pregnancy.

Folic Acid Deficiency: Symptoms and Risks

Folic acid deficiency can cause a variety of health problems. Among the most common symptoms are fatigue, weakness, digestive problems,  and irritability. In the long term, this deficiency can lead to the development of megaloblastic anemia, which is characterized by large, deformed red blood cells that are unable to carry oxygen effectively through the body.

In addition, folic acid deficiency during pregnancy can result in serious complications for the fetus, such as neural tube malformations, premature birth, and low birth weight. To prevent these problems, folic acid supplementation is recommended, especially for women of childbearing age and pregnant women.

What is the Recommended Dose of Folic Acid?

Recommended doses of folic acid vary depending on age, gender, and health conditions. For the general population, the recommended daily allowance of folic acid is 400 micrograms (mcg). However, for women who are planning to become pregnant or who are already pregnant, the recommendation rises to 600 mcg daily.

Some specific groups, such as people with genetic diseases that affect folate metabolism or with nutrient absorption disorders, may need higher doses of folic acid. It is always important to consult a doctor before starting any supplementation.

Folic Acid Supplementation: Who Should Take It?

In addition to pregnant women, other people who may benefit from folic acid supplementation include:

  • People with megaloblastic anemia: Folic acid can help treat and prevent this condition.
  • Individuals with intestinal diseases: Conditions such as celiac disease or Crohn’s disease can interfere with folate absorption, making supplementation necessary.
  • Elderly: With aging, nutrient absorption can decrease, increasing the need for vitamins, including folic acid.

Side Effects and Precautions

While folic acid is generally safe when taken in recommended doses, over-supplementation can mask a vitamin B12 deficiency, a condition that can lead to irreversible neurological damage if left untreated.

Another point to note is that supplementation at very high levels (above 1,000 mcg per day) may not bring additional benefits and, in some cases, may even be harmful. Therefore, it is important to follow medical guidelines regarding dosage.

Conclusion

Folic acid is an essential vitamin for human health, with a critical role in fetal development, the production of red blood cells, and the maintenance of cardiovascular and neurological health. While a balanced diet can provide adequate amounts of folate, supplementation is recommended in some cases, particularly for women who are pregnant or planning to become pregnant.

Maintaining adequate levels of folic acid in the body is essential to ensure full health and avoid problems such as anemia and gestational complications. To ensure adequate intake, it is important to follow a balanced diet and, when necessary, opt for supplementation under medical guidance.