Indole-3-Carbinol (I3C) is a naturally occurring compound derived from the breakdown of glucobrassicin, found in cruciferous vegetables such as broccoli, cabbage, and Brussels sprouts. It is widely studied for its potential to modulate estrogen metabolism and support cellular health, which has implications in hormone balance and detoxification.
In sports and fitness supplementation, I3C may be used to support hormonal health, particularly in individuals interested in optimizing body composition or managing estrogen dominance. It works by influencing the metabolism of estrogen in the liver, leading to a more favorable balance of estrogen metabolites.
Synonyms:
I3C
Benefits:
- Supports hormonal balance (especially estrogen metabolism)
- May aid in liver detoxification pathways
- Potential antioxidant and cellular protection benefits
- May contribute to improved body composition in hormonally sensitive individuals
Sources:
Found in cruciferous vegetables like broccoli, cauliflower, kale, cabbage, and Brussels sprouts.
Observations:
Often used in supplement form as capsules or tablets. Can be taken alone or alongside diindolylmethane (DIM). Excessive doses may cause gastrointestinal upset or dizziness in sensitive individuals.
Related Fields of Study:
Endocrinology, Nutritional Science, Biochemistry, Functional Medicine.