Ornithine is a non-proteinogenic amino acid that plays a key role in the urea cycle, helping to eliminate excess nitrogen from the body. It is naturally produced by the body but is also available as a supplement to support exercise performance and recovery.
It has gained popularity for its potential to reduce fatigue and improve endurance by reducing ammonia accumulation during intense physical activity. Some studies also suggest it may support muscle recovery when used in combination with arginine or citrulline.
Ornithine is particularly relevant for athletes undergoing intense training or endurance events, where managing fatigue and recovery is critical.
Synonyms:
L-Ornithine
Benefits:
- Supports detoxification of ammonia during exercise
- May delay fatigue and enhance endurance
- Aids post-exercise recovery
Sources:
Found in meat, fish, and eggs; also synthesized from arginine.
Observations:
Often combined with citrulline or arginine in pre-workout blends. Typically well-tolerated; excessive doses may cause gastrointestinal issues.
Related Fields of Study:
Exercise biochemistry, Amino acid metabolism, Sports recovery.