Phosphatidylserine

Phosphatidylserine (PS) is a phospholipid component found in the membranes of cells, especially in the brain. It plays a crucial role in maintaining cell structure and signaling, particularly in neurons. As a dietary supplement, PS is used for cognitive enhancement, stress reduction, and improving exercise capacity.

For athletes and fitness enthusiasts, phosphatidylserine has been shown to help reduce exercise-induced cortisol levels, which may support quicker recovery and prevent overtraining-related fatigue.

Its neuroprotective properties also make it a popular ingredient in nootropic and performance-support supplements.

Synonyms:

PS, Phosphatidyl-L-serine

Benefits:

  • Supports cognitive function and memory
  • May reduce exercise-induced cortisol
  • Helps improve focus and mental clarity
  • Promotes recovery and reduces fatigue

Sources:

Naturally found in soy lecithin, egg yolk, and bovine brain (historically); modern supplements use soy- or sunflower-derived sources.

Observations:

Typically used in pre-workout or post-workout stacks, as well as cognitive supplements. Doses around 100–300 mg/day are common. May interact with blood-thinning medications.

Areas of Study Related:

Exercise physiology, Neuroscience, Sports nutrition, Biochemistry.