SAM-e

SAM-e (S-Adenosyl Methionine) is a compound naturally produced in the body, playing a key role in methylation processes, neurotransmitter synthesis, and liver function. As a supplement, SAM-e is often used for mood support, liver health, and joint comfort.

For active individuals, SAM-e may be relevant due to its potential benefits in reducing joint discomfort and improving recovery, particularly in high-impact sports or aging athletes.

It also plays a role in the synthesis of dopamine and serotonin, which can affect motivation and mental resilience during training.

SAM-e contributes to cellular health, and its influence on inflammation and detoxification pathways makes it a versatile support molecule.

Synonyms:

S-adenosylmethionine, Ademetionine

Benefits:

  • May support joint health and reduce exercise-related discomfort
  • Plays a role in mood regulation and mental focus
  • Supports liver detoxification, beneficial during intense supplementation
  • Involved in cellular repair and regeneration

Sources:

Naturally produced in the body; synthesized for supplements through fermentation processes.

Observations:

Available in tablet or enteric-coated form due to sensitivity to degradation. Typical doses range from 200 mg to 1600 mg/day. Excessive use may lead to restlessness or digestive issues. Should not be combined with antidepressant medications without supervision.

Areas of Study Related:

Biochemistry, Neuropsychology, Sports Medicine, Hepatology.